Aceclofenac uses side effects and dosages

What is ACECLOFENAC prescribed for?

This medication is a nonsteroidal anti-inflammatory drug (NSAID). It fights inflammation and pain.

It is used in the symptomatic treatment of osteoarthritis and certain chronic inflammatory rheumatisms (rheumatoid arthritis, ankylosing spondylitis).

You can consult the following article (s):

  • Osteoarthritis and rheumatism
  • Use the usual painkillers well
  • Rheumatoid arthritis
  • Spondylitis

Contraindications of Aceclofenac

This medication should not be used in the following cases:

  • historyof allergy or asthma caused by taking NSAIDs, including aspirin;
  • historyof digestive hemorrhage during previous treatment with NSAIDs ;
  • stomach ulceror duodenum in progress or having recurred;
  • bleeding from the digestive tract or other organ;
  • Cardiovascular disease (heart failure, coronary insufficiency, arteritis, accident vascular brain);
  • severe liver failureor kidney failure ;
  • pregnancy(in the last trimester).


Any prolonged treatment or overdose of NSAIDs exposes to serious undesirable effects .

Certain situations should lead to continuing treatment only after medical advice:

  • severe heartburn or black, foul-smelling stools that may indicate irritation or bleeding from the digestive tract;
  • skin rash withno obvious cause;
  • crisis of asthma;
  • unusual and intense tiredness, or sudden and severe drop in urine volume in a person with heart failure, dehydrated or being treated with a diuretic.

Taking aceclofenac may exhibit an increased risk of cardiovascular events (myocardial infarction or accident vascular cerebral), particularly when used at high doses and for long periods. If you have other cardiovascular risk factors (such as high blood pressure, excess blood cholesterol, diabetes or smoking), tell your doctor.

Precautions are necessary in the elderly and in case of digestive history (ulcer of the stomach or old duodenum), Crohn ‘s disease, ulcerative colitis or asthma.

The NSAIDs have an inhibitory effect on ovulation and may reduce fertility in women. This effect is reversible when treatment is stopped.

Some doctors believe that anti-inflammatory drugs can decrease the effectiveness of intrauterine devices (IUDs) and put them at risk of unwanted pregnancy. This risk is very controversial.

Driver: this drug may be responsible for dizziness.

ACECLOFENAC  interactions with other substances

This medication may interact with the following medications:

  • aspirin (when used in doses greater than 500 mg per dose) and other nonsteroidal anti-inflammatory drugs (NSAIDs): increased risk of ulcer and digestive hemorrhage ;
  • oral and injectable anticoagulants: increased risk of bleeding;
  • the lithium (TÉRALITHE ): increased rate of lithium in the blood;
  • methotrexate (for doses greater than 20 mg per week): risk of increasing the toxicity of methotrexate.

In addition, inform your doctor or pharmacist if you are taking a diuretic, an inhibitor of the enzyme conversion, an angiotensin II, an antiplatelet agent, a corticosteroid, an antidepressant inhibitor of the reuptake of serotonin, a beta blocker or a medicine containing ciclosporin or tacrolimus.

Fertility, pregnancy and lactation

Pregnancy :

Adverse effects on the unborn child have been demonstrated when NSAIDs are used during the last 4 months of pregnancy; the risk exists even with a single take and even if the pregnancy is to term. The use of this medication is contraindicated during this period.

During the first 5 months, the effect of this medicine is poorly understood: only your doctor can assess the possible risk of its use in your case.

Feeding with milk :

The data do not tell whether this medicine passes into breast milk. It is not recommended during breastfeeding.

Instructions for use and dosage of the drug ACECLOFENAC

The tablets should be swallowed with half a glass of water, preferably with meals.

Usual dosage:

  • Adult: 1 tablet, morning and evening.

Do not exceed the dosage or the duration of treatment prescribed by your doctor.


Anti-inflammatory drugs are not harmless drugs. Due to the possibility of serious side effects, they should only be used when necessary, which is not the case for mild pain conditions and mild trauma.

This medication has been prescribed for you in a specific situation: do not recommend it to a loved one and do not reuse it without medical advice.

Possible side effects of the drug ACECLOFENAC

The most common side effects are digestive: nausea, vomiting, diarrhea, bloating, constipation, abdominal pain, gastritis, worsening of Crohn ‘s disease or ulcerative colitis. More rarely: ulcer of the stomach or duodenum, especially in case of high dose treatment, prolonged use and in the elderly. Exceptionally: bleeding from the digestive tract (bloody vomiting, black stools or more often imperceptible blood loss, responsible for the appearance of anemia).

Uncommon: rash, hives, itching; exceptionally, severe skin allergy (bullous rashes).

Rarely: high blood pressure, edema, blurred vision.

Very rarely: tingling, tremors, drowsiness, altered taste, headache, depression, abnormal dreams, dizziness, ringing in the ears, palpitations, flushing, weight gain, fatigue, leg cramps, hepatitis, pancreatitis, allergic reaction (asthma attack, angioedema, anaphylactic shock), increased transaminases, abnormal blood count.

Water retention that can worsen heart failure.

Studies have also shown an increased risk of myocardial infarction.

You have experienced an undesirable effect likely to be due to this medicine, you can report it online.

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